Fluorescence spectroscopy using indocyanine green for lymph node mapping [Elektronisk resurs]
-
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII, 2-4 February 2014, San Francisco, California, USA
-
Haj-Hosseini, Neda (författare)
-
Behm, Pascal (författare)
-
Shabo, Ivan (författare)
-
Wårdell, Karin, 1959- (författare)
-
MINT (medarbetare)
-
MINT (medarbetare)
-
Linköpings universitet Institutionen för medicinsk teknik (utgivare)
-
Linköpings universitet Tekniska högskolan (utgivare)
-
Linköpings universitet Institutionen för medicinsk teknik (utgivare)
-
Linköpings universitet Institutionen för klinisk och experimentell medicin (utgivare)
-
Linköpings universitet Hälsouniversitetet (utgivare)
-
Östergötlands Läns Landsting Centrum för kirurgi, ortopedi och cancervård (utgivare)
- Publicerad: 2014
- Engelska.
-
Ingår i: Proceedings of SPIE, the International Society for Optical Engineering. - 0277-786X. ; 8935:893504, 1-6
-
Läs hela texten
-
Läs hela texten
-
Läs hela texten
-
Läs hela texten
- Relaterad länk:
-
http://www.liu.se (web site)
Sammanfattning
Ämnesord
Stäng
- The principles of cancer treatment has for years been radical resection of the primary tumor. In the oncologic surgeries where the affected cancer site is close to the lymphatic system, it is as important to detect the draining lymph nodes for metastasis (lymph node mapping). As a replacement for conventional radioactive labeling, indocyanine green (ICG) has shown successful results in lymph node mapping; however, most of the ICG fluorescence detection techniques developed are based on camera imaging. In this work, fluorescence spectroscopy using a fiber-optical probe was evaluated on a tissue-like ICG phantom with ICG concentrations of 6-64 μM and on breast tissue from five patients. Fiber-optical based spectroscopy was able to detect ICG fluorescence at low intensities; therefore, it is expected to increase the detection threshold of the conventional imaging systems when used intraoperatively. The probe allows spectral characterization of the fluorescence and navigation in the tissue as opposed to camera imaging which is limited to the view on the surface of the tissue
Ämnesord
- Engineering and Technology (ssif)
- Medical Engineering (ssif)
- Teknik (ssif)
- Medicinteknik (ssif)
Genre
- government publication (marcgt)
Indexterm och SAB-rubrik
- Intra-operative optical imaging
- near infrared fluorescence
- breast cancer surgery
- optical phantom
- optimal ICG concentration
- spectroscopy
Inställningar
Hjälp
Ingår i annan publikation. Gå till titeln
Proceedings of SPIE, the International Society for Optical Engineering