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Youth with severe mental illness and complex non-somatic motor abnormalities : conflicting conceptualizations and unequal treatment

Peter Andersson (Author), Lee E. Wachtel (Author), Johan Lundberg (Author), Esmail Jamshidi (Author), Johan Bring (Author)
URI https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-239643, URN urn:nbn:se:umu:diva-239643, DOI 10.1038/s44184-022-00013-8
Umeå universitet Medicinska fakulteten (Publisher), Umeå universitet Medicinska fakulteten (Publisher)
publication
Nature Publishing Group, 2022
Is part of
npj Mental Health Research
1:1
Component part, Online resource
Subject
Medical and Health Sciences, Clinical Medicine, Psychiatry, Medicin och hälsovetenskap, Klinisk medicin, Psykiatri

Summary

Two emerging diagnostic concepts promote distinct treatments for youth with acute-onset motor abnormalities and severe concurrent psychiatric symptoms: Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric catatonia. Both have institutional approval in parts of Europe and in the USA, meriting an unconditional comparison of supporting evidence. Here we report results of qualitative and quantitative analyses of literature and Swedish National Registry Data suggesting that (1) catatonic patients are liable to fulfilling diagnostic criteria for PANS, (2) three conservatively assessed PANS case-reports present with possible unrecognized catatonia, (3) lithium and electroconvulsive therapy usage frequencies in Swedish minors (exclusively recommended for severe mental illness) are strongly intercorrelated and unequally distributed across Swedish counties, (4) established severe mental disorders are rarely overtly considered amongst PANS-specific research and (5) best-available evidence treatments appear markedly superior for pediatric catatonia compared to PANS in both childhood and adolescence. Prioritizing treatments for pediatric catatonia in concerned subjects could markedly improve treatment outcomes.

Details

Contributor and role
Peter Andersson (Author), Lee E. Wachtel (Author), Johan Lundberg (Author), Esmail Jamshidi (Author), Johan Bring (Author)
Contributor and role
Umeå universitet Medicinska fakulteten (Publisher), Umeå universitet Medicinska fakulteten (Publisher)
Identifier
URI https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-239643, URN urn:nbn:se:umu:diva-239643, DOI 10.1038/s44184-022-00013-8
Title resource
Youth with severe mental illness and complex non-somatic motor abnormalities : conflicting conceptualizations and unequal treatment
Is part of
npj Mental Health Research
Part
1:1
publication
Nature Publishing Group, 2022
Relaterad beskrivning eller innehåll
Värdpublikation
Note
  • Published
Use and access condition
gratis
in bibliography
control number
3n0frlzb1tqtv5q0