Gut microbiota peculiarities in aged HIV-infected individuals : molecular understanding and therapeutic perspectives /Ramachandran Vignesh, Pitchaipillai S. Ganesh, Sathish Sankar, Indranil Chattopadhyay, Yean K. Yong, Marie Larsson & Esaki M. Shankar.

Aging is a progressive physiological process that involves alterations in the population of normal gut microbiota. HIV infection in conjunction with aging complicates the quality of immune responses paving way for increased epithelial permeability and translocation of commensals and pathogen-derived substances into the systemic circulation. Enteric dysbiosis is linked with other comorbidities of aging including cardiovascular diseases and dementia in the HIV-infected population. The diversity of gut microbiota declines with age, and HIV infection compromises the effective functioning of the immune system complicating the metabolic as well as regulatory programming of the host’s physiological machinery. Given the scenario of the global HIV/AIDS and the COVID-19 pandemics, it is also likely that alterations in gut microbiota potentially could contribute to post-acute COVID-19 syndrome as well as accelerate the rate of HIV disease progression. The current chapter discusses the role of normal gut microbiota in the aged HIV-infected population and their functional implications in normal cellular and molecular mechanisms in the host.

Ingår i:Marotta, Francesco.Gut Microbiota in Aging and Chronic DiseasesSidorna 415-4399783031140235

Inställningar Hjälp

Fler titlar av: Vignes, Ramachandran; Ganesh, Pitchaipilla ...; Sankar, Sathish; Chattopadhyay, Indra ...; Yong, Yean K.; Larsson, Marie, 1966 ...; visa fler...; Shankar, Esaki M.; visa färre...
Ingår i: Marotta, Francesco.: ...; Fler artiklar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst. Hantera kakor.