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Classification of ≥80-year-old individuals into healthy, moderately healthy, and frail based on different frailty scores affects the interpretation of laboratory results

Maria Edvardsson (Författare), Märtha Sund-Levander, 1954- (Författare), Anna Milberg, 1966- (Författare), Jan Ernerudh, 1952- (Författare), Ewa Wressle, 1953- (Författare)

URI http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-192092, URN urn:nbn:se:liu:diva-192092, DOI 10.3126/ajms.v13i9.45298, Identifikator http://liu.diva-portal.org/smash/get/diva2:1740589/FULLTEXT01 · url

Linköpings universitet Medicinska fakulteten (Utgivare), Linköpings universitet Institutionen för hälsa, medicin och vård (Utgivare), Linköpings universitet Institutionen för hälsa, medicin och vård (Utgivare), Linköpings universitet Institutionen för biomedicinska och kliniska vetenskaper (Utgivare), Linköpings universitet Institutionen för hälsa, medicin och vård (Utgivare)

utgivning

Nepal Journals Online (NepJOL), 2022

är del av

Asian Journal of Medical Sciences · ISSN 2091-0576

13:9, 63-71

Bidrag, Onlineresurs

Finns online:

http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-192092

Värdpublikation

ämne

Medical and Health Sciences, Clinical Medicine, Geriatrics, Medicin och hälsovetenskap, Klinisk medicin, Geriatrik, Medical and Health Sciences, Clinical Medicine, Clinical Laboratory Medicine, Medicin och hälsovetenskap, Klinisk medicin, Klinisk laboratoriemedicin, Aging; Frail elderly; Analyte; Reference interval; Clinical interpretation

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Sammanfattning

Background: Interpretation laboratory analyses are crucial when assessing the patient’s condition. Reference intervals from apparently healthy and disease-free individuals may cause problems when outcomes from elderly patients with chronic diseases and on medications are being interpreted. Elderly individuals are a heterogeneous group ranging from individuals managing their daily life independently to individuals with diseases and impairment, in need of nursing care around the clock, that is, frail; a term widely used although there is no consensus on the definition. Aims and Objectives: The aim of the study was to study the effect of classification of elderly into healthy, moderately healthy, and frail, based on activities of daily living (ADL) and Mini-Mental State Examination (MMSE) or frailty index (FI), on the interpretation of outcomes regarding: Albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, and gamma-glutamyltransferase (γ-GT) levels. Materials and Methods: Individuals ≥80 years (n=568) were classified either on ADL and MMSE or number of deficits, (FI). Results: Individuals classified as frail based on FI had lower mean levels for ALT, creatinine and γ-GT than individuals classified based on ADL and MMSE (P<0.05). Conclusion: The model to define health status to some extent affected laboratory analyte levels in ≥80 years old, classified as healthy, moderately healthy, and frail based on ADL and MMSE versus FI.

Detaljer

Medverkan och funktion

Maria Edvardsson (Författare), Märtha Sund-Levander, 1954- (Författare), Anna Milberg, 1966- (Författare), Jan Ernerudh, 1952- (Författare), Ewa Wressle, 1953- (Författare)

Medverkan och funktion

Identifikator

har titel

Classification of ≥80-year-old individuals into healthy, moderately healthy, and frail based on different frailty scores affects the interpretation of laboratory results