Finding cells, finding molecules, finding patterns [Elektronisk resurs]

• Many modern molecular labeling techniques result in bright point signals. Signals from molecules that are detected directly inside a cell can be captured by fluorescence microscopy. Signals representing different types of molecules may be randomly distributed in the cells or show systematic patterns indicating that the corresponding molecules have specific, non-random localizations and functions in the cell. Assessing this information requires high speed robust image segmentation followed by signal detection, and finally pattern analysis. We present and discuss this type of methods and show an example of how the distribution of different variants of mitochondrial DNA can be analyzed. 

Ämnesord

Natural Sciences  (hsv)

Computer and Information Sciences  (hsv)

Computer Sciences  (hsv)

Naturvetenskap  (hsv)

Data- och informationsvetenskap  (hsv)

Datavetenskap (datalogi)  (hsv)

SOCIAL SCIENCES  (svep)

Statistics, computer and systems science  (svep)

Informatics, computer and systems science  (svep)

Data processing  (svep)

SAMHÄLLSVETENSKAP  (svep)

Statistik, data- och systemvetenskap  (svep)

Informatik, data- och systemvetenskap  (svep)

Databehandling  (svep)

Indexterm och SAB-rubrik

mass data analysis; image analysis; cytometry; single molecule detection; padlock probes; pattern analysis.